As Lukasoh said I already hosted a german region tournament the last October and November with 10 teams, 95 players, and 4 weeks group stage + 3 weeks knockouts. In my opinion, it went extremely good although I think I personally only did a medium good job with hosting it.
But I agree with a lot Herishey has said. Not a lot of national communities have the activity and the effort to do something. I have for myself considered trying to get a french host on board for cooperation but couldn't really decide for myself already.
For myself, I am planning to host a second version of the german tournament in September-October, so basically 1 year after season 1. I doubt any really big approach could be succesful.